Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Paper | Regular issue | Vol 71, No. 4, 2007, pp.891-902
Published online, 21st February, 2007
DOI: 10.3987/COM-07-11001
Synthesis of Mexiletine Analogues from Non-Activated Aziridines

Truls Ingebrigtsen and Tore Lejon*

*Faculty of Science, Department of Chemistry, University of Tromsø, N-9037 Tromsø, Norway


A general method for the synthesis of mexiletine analogues by nucleophilic ring opening of non-activated racemic aziridines has been developed (Scheme 1). Structural variation is introduced by employing different nucleophiles or by altering the substitution on the aziridine ring.