Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Communication | Special issue | Vol 70, No. 1, 2006, pp.57-64
Published online, 25th July, 2006
DOI: 10.3987/COM-06-S(W)9
Titanium Tetraiodide Mediated Reductive Opening of Aziridines, Leading to the Aldol and Mannich-Type Reactions

Makoto Shimizu,* Hiroshi Kurokawa, Shuji Nishiura, and Iwao Hachiya

*Department of Chemistry for Materials, Faculty of Engineering, Mie University, 1577 Tsu, Mie 514-8507, Japan


Reductive ring-opening of N-tosylazirindes was readily carried out with titanium tetraiodide to form the titanium enolates, which in turn were subjected to addition reaction with aldehydes or imines to give aldol or Mannich-type products in good yields.