Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact: purchase@heterocycles.com

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Note | Special issue | Vol 70, No. 1, 2006, pp.541-548
Published online, 11th July, 2006
DOI: 10.3987/COM-06-S(W)6
Chiral Synthesis of Poison-Frog Alkaloids 251N and 221K

Naoki Toyoooka,* Zhou Dejun, Hideo Nemoto,* H. Martin Garraffo, Thomas F. Spande, and John W. Daly

*Faculty of Pharmaceutical Sciences, Toyama University, 2630 Sugitani, Toyama, Toyama 930-0194, Japan

Abstract

The chiral synthesis of 8-butyl 5-substituted poison-frog alkaloids 251N and 221K has been achieved, and the relative stereochemistry of natural 251N was determined by the present chiral synthesis.