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Paper | Regular issue | Vol 71, No. 4, 2007, pp.847-854
Published online, 1st February, 2007
DOI: 10.3987/COM-06-10985
Copper(I) Iodide-Catalyzed Coupling Reaction of Haloindoles with α-Amino Acids

Masayuki Kurokawa, Waka Nakanishi, and Tsutomu Ishikawa*

*Graduate School of Pharmaceutical Sciences, Chiba University, 1-33 Yayoi, Inage, Chiba 263-8522, Japan


Copper (I) iodide-catalyzed amination of haloindoles with amino acids using a combination of Cs2CO3 in DMSO was explored. Amino acid derivatives with indole skeleton were smoothly afforded in moderate yields.