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Communication | Regular issue | Vol 68, No. 12, 2006, pp.2471-2476
Published online, 2nd November, 2006
DOI: 10.3987/COM-06-10891
Synthesis of Chiral Non Racemic Indolizidin-3-ones as Peptidomimetic Scaffold

Delphine Halie, Joëlle Pérard-Viret, and Jacques Royer*

*Faculty of Pharmacy, UMR 8638 (CNRS-University Paris 5), 4 Avenue de l’Observatoire, 75270 Paris Cedex 06, France


A new asymmetric strategy has been devised to attain indolizidin-3-ones wich can be used as peptidomimetic scaffolds. The sequence is a two-step synthesis.