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Obituary
Yoshito Kishi (1937-2023)
Yoshito Kishi (1937-2023)
Professor. Yoshito Kishi,
a member of the Honorary Editorial Associates of HETEROCYCLES,
has passed away on January 9, 2023 at the age of 85.
I deeply express my regret over his death.
Kunio Ogasawara
Editor
January 13, 2023
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Paper | Regular issue | Vol 68, No. 11, 2006, pp.2327-2333
Published online, 22nd September, 2006■ L-Proline-Catalyzed Asymmetric Aldol Condensation of N-Substituted Isatins with Acetone
Published online, 22nd September, 2006
DOI: 10.3987/COM-06-10856
■ L-Proline-Catalyzed Asymmetric Aldol Condensation of N-Substituted Isatins with Acetone
Gang Chen, Ye Wang, Hongping He, Suo Gao, Xiaosheng Yang, and Xiaojiang Hao*
*State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, PR China
Abstract
L-proline-catalyzed asymmetric aldol condensation of several isatin derivatives with acetone is reported. The desired products were obtained in highly yield with the ee among 30-79%. The substitutes of N can deeply effect the ee value of products, and a novel mechanism is also described.
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