Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Communication | Regular issue | Vol 68, No. 10, 2006, pp.2031-2036
Published online, 1st August, 2006
DOI: 10.3987/COM-06-10837
Synthesis of Vigabatrin®

Meng-Yang Chang,* Chun-Yu Lin, and Chi-Wi Ong

*Department of Applied Chemistry, National University of Kaohsiung, Kaohsiung 811, Taiwan, R.O.C.


A concise synthesis of vigabatrin® has been achieved from trans-(2S,4R)-4-hydroxyproline via the key regioselective Baeyer-Villiger lactonization reaction.