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Note | Regular issue | Vol 68, No. 8, 2006, pp.1715-1722
Published online, 20th June, 2006
DOI: 10.3987/COM-06-10782
Synthesis of Substituted Aminoquinolines as Useful Intermediates for Preparation of Aromatic N-Tricyclic Systems

Antonio Carta,* Michele Palomba, and Paola Corona

*Department of Medicinal and Toxicological Chemistry, University of Sassari, Via Muroni 23, 07100 Sassari, Italy

Abstract

An effective approach for the synthesis of new substituted mono and diaminoquinolines is described. Two known quinolines 7,8-dichloro-6-nitroquinoline (1) and 7,8-dichloro-6-nitrohydroquinolin-4-one (9) were used as key intermediates.