Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Communication | Regular issue | Vol 68, No. 8, 2006, pp.1559-1564
Published online, 23rd June, 2006
DOI: 10.3987/COM-06-10762
A Facile and Convenient Synthesis of 1H-Isoindole-1,3(2H)-diones

Farzad Nikpour,* Samira Kazemi, and Davood Sheikh

*Department of Chemistry, Faculty of Sciences, University of Kurdistan, Sanandaj, Pasdaran Bivd., P.O.Box 66135-416, Iran


A facile synthesis of 1H-isoindole-1,3(2H)-diones (3a-h) has been developed by the reaction of the corresponding anhydrides (1a-h) with potassium cyanate (4a) or sodium thiocyanate (4b). The reactions were carried out in neutral media under reflux or under microwave irradiation without use of catalyst. Good to excellent yields of the products were obtained in high purity with very simple work-up.