Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Paper | Regular issue | Vol 68, No. 6, 2006, pp.1185-1190
Published online, 25th April, 2006
DOI: 10.3987/COM-06-10722
An Convenient Method for the Synthesis of 7,8-Dimethoxy-3-hydroxyquinolin-2(1H)-one and Its Tautomer Conformation Study

Jian Song, Yongcheng Lin,* Yau Shan Szeto, and Wing Lai Chan*

*School of Chemistry and Chemical Engineering, Sun Yat-sen University, Guangzhou 510275, China


3-Hydroxyquinolin-2(1H)-one (1) was synthesized successfully from readily available 2-nitroveratraldehyde in a three-step reaction. The procedure was based on existing protocol but with slight modification to give a much higher production yield. The tautomer conformation of the quinolinone was studied.