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Obituary
Yoshito Kishi (1937-2023)
Yoshito Kishi (1937-2023)
Professor. Yoshito Kishi,
a member of the Honorary Editorial Associates of HETEROCYCLES,
has passed away on January 9, 2023 at the age of 85.
I deeply express my regret over his death.
Kunio Ogasawara
Editor
January 13, 2023
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Paper | Regular issue | Vol 68, No. 6, 2006, pp.1185-1190
Published online, 25th April, 2006■ An Convenient Method for the Synthesis of 7,8-Dimethoxy-3-hydroxyquinolin-2(1H)-one and Its Tautomer Conformation Study
Published online, 25th April, 2006
DOI: 10.3987/COM-06-10722
■ An Convenient Method for the Synthesis of 7,8-Dimethoxy-3-hydroxyquinolin-2(1H)-one and Its Tautomer Conformation Study
Jian Song, Yongcheng Lin,* Yau Shan Szeto, and Wing Lai Chan*
*School of Chemistry and Chemical Engineering, Sun Yat-sen University, Guangzhou 510275, China
Abstract
3-Hydroxyquinolin-2(1H)-one (1) was synthesized successfully from readily available 2-nitroveratraldehyde in a three-step reaction. The procedure was based on existing protocol but with slight modification to give a much higher production yield. The tautomer conformation of the quinolinone was studied.
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