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Note | Regular issue | Vol 65, No. 10, 2005, pp.2493-2503
Published online, 12th August, 2005
DOI: 10.3987/COM-05-10485
One-pot Synthesis of trans-7-Aryl-6H-6a,7-dihydro[1]benzopyrano[3,4-c][1,5]benzothiazepines

Ramadas Sathunuru, Benjamin Koh, Hongming Zhang, and Ed Biehl*

*Chemistry Department, Southern Methodist University, Dallas, TX 75275-0314, U.S.A.


Green chemical approaches for the condensation reaction of benzenethiols and 3-arylidenenchroman-4-ones as synthons for the synthesis of a series of newtrans-7-aryl-6H-6a,7-dihydro[1]benzo pyrano[3,4-c][1,5]benzo- thiazepines which may possess potential biological activity are described.