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Note | Regular issue | Vol 65, No. 11, 2005, pp.2741-2751
Published online, 19th August, 2005
DOI: 10.3987/COM-05-10461
Synthesis of Substituted 1,3-Dimethyl-1H-quinoxalin-2-ones from Aniline Derivatives

Xun Li, Donghua Wang, Jifeng Wu, and Wenfang Xu*

*College of Pharmacy, Shangdong University, Jinan 250012, China


Substituted 1,3-dimethyl-1H-quinoxalin-2-ones (7) have been synthesized through the procedures of acylation, nitration, reduction, intramolecular alkylation, oxidation, and N-methylation starting from 3,4-disubstituted aniline.