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Communication | Regular issue | Vol 65, No. 8, 2005, pp.1811-1815
Published online, 28th June, 2005
DOI: 10.3987/COM-05-10443
Three New Synthetic Methods for the 1,2,3,3a,8,8a-Hexahydropyrrolo[2,3-b]indoles Having an Alkoxy Group at the 3a-Position

Takako Iwaki, Fumio Yamada, Shiho Funaki, and Masanori Somei*

*Division of Pharmaceutical Sciences, Graduate School of Natural Science and Technology, Kanazawa University, Kakuma, Kanazawa, Ishikawa 920-1192, Japan


Three methods have been newly developed for the synthesis of 1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indoles. Employing them, 3a-chloro-, 3a-bromo-, 3a-hydroxy-, and various 3a-alkoxy-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indoles are now readily available.