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Paper | Regular issue | Vol 65, No. 8, 2005, pp.1925-1929
Published online, 1st July, 2005
DOI: 10.3987/COM-05-10442
Total Synthesis of Styelsamine C, and Formal Synthesis of Norsegoline

Shinsuke Nakahara* and Akinori Kubo

*Meiji Pharmaceutical University, 2-522-1 Noshio, Kiyose, Tokyo 204-8588, Japan

Abstract

Two fused tetracyclic aromatic alkaloids, styelsamine C (3) from the ascidian Eusynstyela latericius, and norsegoline (5) from the marine tunicate Eudistoma sp., were synthesized using a biaryl cross-coupling reaction.