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Paper | Regular issue | Vol 65, No. 8, 2005, pp.1881-1887
Published online, 10th June, 2005
DOI: 10.3987/COM-05-10433
New Syntheses of 1-Benzoyltetrahydroisoquinoline Derivatives Using Polymer-supported Bis(trifluoroacetoxyiodo)benzene

Hsin-Yu Huang, Rei-Sheu Hou, Huey-Min Wang, and Ling-Ching Chen*

*Graduate Institute of Pharmaceutical Sciences, Kaohsiung Medical University, 100 Shin Chuan 1st Rd., Kaohsiung 80708, Taiwan, R.O.C.


The reaction of N-benzenesulfonyl-β-phenethylamines with α-benzoyl sulfides using polymer-supported bis(trifluoroacetoxyiodo)benzene (PSBTI) gives moderate to good yields of the corresponding 1-benzoyltetrahydroisoquinoline derivatives.