Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact: purchase@heterocycles.com

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Paper | Regular issue | Vol 65, No. 9, 2005, pp.2061-2070
Published online, 5th August, 2005
DOI: 10.3987/COM-05-10387
Synthesis and Antitumor Activity of 2-Aryl-7-fluoro-6-(4-methyl-1-piperazinyl)-4(3H)-quinazolinones

Raid J. Abdel-Jalil,* Hani M. Aldoqum, Mikdad T. Ayoub, and Wolfgang Voelter*

*Abteilung für Physikalische Biochemie, Physiologisch-chemisches Institut, Universität Tübingen, Hoppe-Seyler-Sraβe 4, D-72076 Tübingen, Germany

Abstract

A series of new 2-aryl-7-fluoro-6-(4-methyl-1-piperazinyl)-4(3H)-quinazolinones were prepared by the oxidative cyclization of the corresponding 2-arylidineamino-4-fluoro-5-(4-methyl-1-piperazinyl)benzamides. The new quinazolinones were evaluated for their antitumor activity.