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■ Flavone C-Glycosides from Isatis tinctoria Leaves

Yongxian Cheng, Bernd Schneider, Christine Oberthür, Heidemarie Graf, Sven Adler, and Matthias Hamburger*

*Department of Pharmaceutical Sciences, University of Basel, Klingelbergstrasse 50, CH-4056 Basel, Switzerland

Abstract

Two new flavone C-glycosides, chrysoeriol 6-C-β-D-glucopyranosyl- (1→3)-β-glucopyranoside (1) and apigenin 6-C-β-D-glucopyranosyl-(1→3)-β-glucopyranoside (2) were isolated from a methanolic extract of Isatis tinctoria leaves and identified on the basis of spectral analysis and hydrolysis. Two known flavone C-glycosides, isoscoparin (3) and isovitexin (4), were also identified.