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Paper | Special issue | Vol 64, No. 1, 2004, pp.121-128
Published online, 12th March, 2004
DOI: 10.3987/COM-04-S(P)4
A Flexible Approach to (S)-3-Amino-2-pyrrolidinone Derivatives

Tian Tang, Chen Zhu, and Pei-Qiang Huang*

*Department of Chemistry, Xiamen University, 422 Siming Nanlu, Xiamen, Fujian 361005, China


Starting from (S)-aspartic acid, a flexible chemoselective approach to (S)-3-amino-2-pyrrolidinone derivatives was reported. The (S)-3-amino-2-pyrrolidinone derivatives thus synthesized are useful templates for designing medicinal interesting compounds.