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Paper | Special issue | Vol 64, No. 1, 2004, pp.215-221
Published online, 29th June, 2004
DOI: 10.3987/COM-04-S(P)14
Antileishmanial Activities of Rhodacyanine Dyes

Kiyosei Takasu,* Hiroki Terauchi, Hiroshi Inoue, Marii Takahashi, Setsuko Sekita, and Masataka Ihara*

*Graduate School of Pharmaceutical Sciences, Tohoku University, Aramaki, Aoba-ku, Sendai 980-8578, Japan

Abstract

Rhodacyanine dyes, potent antimalarial agents, was found to possess strong antileishmanial activity against Leishmania major in vitro. The efficacies of several compounds are comparable to one of clinically used amphotericin B.