HETEROCYCLES
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Note | Regular issue | Vol 65, No. 4, 2005, pp.857-863
Published online, 25th February, 2005■ Withanolides from Datura innoxia
Published online, 25th February, 2005
DOI: 10.3987/COM-04-10256
■ Withanolides from Datura innoxia
Bina S. Siddiqui,* Shamsul Arfeen, Farhana Afshan, and Sabira Begum
*International Centre for Chemical Sciences, H. E. J. Research Institute of Chemistry, University of Karachi, Karachi-75270, Pakistan
Abstract
The methanolic extract of the aerial parts of Datura innoxia afforded two new withanolides namely witharifeen (1) and daturalicin (2). Their structures were established as 11α, 12β-dihydroxy (20R, 22R)-21,24-epoxy-1-oxowitha-2, 5, 25(27)-trien-22, 26-olide (1) and (20R, 22R)-5β, 6β -14α,15α -21,24-triepoxy-1-oxowitha-2,25(27)-dien-22,26-olide (2) respectively by analysis of spectroscopic data.
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