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■ Syntheses of Pyrrolo- and Furo-1,4-dihydropyridine Derivatives

Keizo Matsuo,* Masami Adachi, Tatsuko Takagi, Sachiko Ueno, Takahiko Arase, and Fumie Kuroi

*Faculty of Pharmaceutical Sciences, Kinki University, Kinki University, 3-4-1, Kowakae, Higashi-Osaka 577-8502, Japan

Abstract

Methyl 4-aryl-1,4,5,7-tetrahydro-2,7,7-trimethyl-5-oxo-6H-pyrrolo[4,3-b]pyridine-3-carboxylates and methyl 1,4,5,7-tetrahydro-3-methyl-7-oxo-4-phenylfuro[3,4-b]pyridine-3-carboxylate were synthesized. Attempting synthesis of methyl 4-aryl-1,3,5,7a-tetrahydro-1,1,6-trimethyl-3-oxofuro[3,4-c]pyridine-7-carboxylates failed.