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Note | Regular issue | Vol 65, No. 1, 2005, pp.173-179
Published online, 2nd November, 2004
DOI: 10.3987/COM-04-10226
Stilbenoids from Leaves of Upuna borneensis

Tetsuro Ito,* Ibrahim Iliya, Toshiyuki Tanaka, Ken-ichi Nakaya, Yukihiro Akao, Yoshinori Nozawa, Jin Murata, Dedy Darnaedi, and Munekazu Iinuma

*Gifu Prefectrual Institute of Health and Environmental Sciences


An acetone extract of the leaves of Upuna borneensis afforded two stilbene tetramer derivatives (upunaphenols F and G) together with four stilbenoids (vaticanols B and C, piceid and cis-piceid). The structures and their relative stereochemistry were determined by spectroscopic techniques, in particular by using 2D NMR method. Upunaphenol G was found to suppress cell growth in HL60 cells with IC50 at 15.6 μM.