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Note | Regular issue | Vol 65, No. 1, 2005, pp.165-171
Published online, 29th November, 2004
DOI: 10.3987/COM-04-10224
Preparation of New Vindoline Derivatives by Palladium-catalyzed Cross-Coupling Reaction

Melinda Fekete, Pal Kolonits, and Lajos Novak*

*Institute for Organic Chemistry, Budapest University of Technology and Economics, H-1111 Budapest, Gellert ter 4, Hungary

Abstract

A new series of aryl-substituted vindoline derivatives (3) was prepared by palladium-catalyzed cross-coupling reaction of 15-iodovindoline (1c) with arylboronic acids (2).