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Paper | Regular issue | Vol 63, No. 9, 2004, pp.2013-2017
Published online, 3rd August, 2004
DOI: 10.3987/COM-04-10121
KAl(SO4)2·12H2O: An Efficient Catalyst for the Stereoselective Synthesis of cis-Isoquinolonic Acids

Javad Azizian,* Ali A. Mohammadi, Ali R. Karimi, Mohammad R. Mohammadizadeh, and M. Koohshari

*Department of Chemistry, Faculty of Science, Shahid Beheshti University, P. O. Box 19395-4716 Tehran, Iran


KAl(SO4)2·12H2O is found to catalyze efficiently the stereoselective cyclocondensation of homophthlic anhydride with imines under mild conditions to afford the corresponding cis-isoquinolonic acids in good yields.