Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Paper | Regular issue | Vol 63, No. 11, 2004, pp.2457-2463
Published online, 1st October, 2004
DOI: 10.3987/COM-04-10095
Synthesis of 4-Methoxybenzylamino Derivatives of Dibenzothiadiazepinedioxide

Nicolas Lebegue,* Sebastien Gallet, Nathalie Flouquet, Pascal Carato, Stéphanie Giraudet, and Pascal Berthelot

*Laboratoire de Chimie Thérapeutique, Faculté des Sciences Pharmaceutiques et Biologiques de Lille, Université de Lille 2, 3, rue du Professeur Laguesse, BP 83, F-59006 Lille, France


This article reports the synthesis of new dibenzothiadiazepinedioxides bearing a 4-methoxybenzylamino group at 8- or 9-C position of the tricyclic heterocycle. Construction of the 8- or 9-aminodibenzothiadiazepinedioxide is achieved via Weber’s method and the 4-methoxybenzyl analogues are realized by reductive amination using 4-anisaldehyde.