Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact: purchase@heterocycles.com

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Paper | Regular issue | Vol 63, No. 6, 2004, pp.1359-1374
Published online, 9th April, 2004
DOI: 10.3987/COM-04-10057
Intramolecular Pauson-Khand Reaction of 3-Alkynyl-1-alkylidenecycles: A Convenient Synthesis of [5.n.1.01,5] Tricyclic Compounds

Miyuki Ishizaki,* Mina Masamoto, Osamu Hoshino, Kiyoshi Nishitani, and Hiroshi Hara*

*Faculty of Pharmaceutical Sciences, Science University of Tokyo, 2641 Yamazaki, Noda, Chiba 278-8510, Japan

Abstract

An intramolecular Pauson-Khand reaction of various 3-alkynyl-1-alkylidenecyclic compounds was performed to give the corresponding [5.n.1.01,5] tricyclic compounds (n = 2-4). A facile construction of the core structure in cedrene terpenoids was also investigated in detail and formal total synthesis of α- and β-cedrenes was accomplished.