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Paper | Regular issue | Vol 63, No. 5, 2004, pp.1083-1091
Published online, 5th March, 2004
DOI: 10.3987/COM-04-10021
Synthesis of Fluorescent Derivatization Reagents: Reaction of Isatin with 3-Aryl-7-diethylaminocoumarins and Their Fluorescent Properties

Naozumi Nishizono,* Kazuaki Oda, Yutaka Kato, Kosei Ohno, Masaru Minami, and Minoru Machida

*Faculty of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Hokkaido 061-0293, Japan

Abstract

Fluorescent derivatization reagents, 3-aryl-7-diethylaminocoumarin derivatives, were synthesized and reacted with isatin to give the adduct. Their fluorescent properties are discussed.