Online article for Non-subscribers

Pay per view

Heterocycles has a pay-per-view service for Non-subscribers.
You will be able to directly purchase the full text article through PayPal.
Your purchased Paper can be downloaded after the payment is completed.
An e-mail will be sent the URL to download the paper.
If you have any questions, please contact:

Price: ¥ 4,400 (Yen only)
Period: This Article can be accessed for 7 days.

Communication | Special issue | Vol 61, No. 1, 2003, pp.87-92
Published online, 6th October, 2003
DOI: 10.3987/COM-03-S46
Enantioselective Synthesis of the G-Ring of Brevetoxin A

Michael T. Crimmins* and Pamela A. Cleary

*Department of Chemistry, CB 3290, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-3290, U.S.A.


An enantioselective synthesis of the eight-membered G-ring of brevetoxin A is described. The synthesis exploits a ring-closing metathesis reaction to construct the eight-membered ether ring. The stereochemistry of the α and α’ centers of the ether linkage were established through a Sharpless kinetic resolution and an asymmetric glycolate alkylation reaction.