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Note | Regular issue | Vol 63, No. 5, 2004, pp.1165-1173
Published online, 24th February, 2004
DOI: 10.3987/COM-03-9997
A Solvent-free Method for Substituted Imidazolidin-4-ones Synthesis

Jirí Pospísil and Milan Potácek*

*Department of Organic Chemistry, Faculty of Science, Masaryk University, Kotlárská 2, CZ-61137 Brno, Czech Republic


A new method of the solvent-free synthesis of substituted imidazolidin-4-ones is described. The method is developed for microwave-assisted solvent-free conditions and compared with classical thermally initiated solvent-free conditions. In both cases the reaction proceeds with good yields. However, the reaction under microwave conditions is accelerated six-times. Thermal effect of the microwaves is observed.