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Note | Regular issue | Vol 60, No. 8, 2003, pp.1891-1897
Published online, 30th June, 2003
DOI: 10.3987/COM-03-9789
Facile Synthesis of Diarylpyrazines Using Suzuki Coupling of Dichloropyrazines with Aryl Boronic Acids

Nate Schultheiss and Eric Bosch*

*Department of Chemistry, Southwest Missouri State University, 901 South National Avenue, Springfield, MO 65804, U.S.A.


The palladium-catalyzed coupling of dichloropyrazines with aryl boronic acids is reported. The reaction proceeds smoothly under anaerobic conditions to give moderate to good yields of the corresponding diarylpyrazines.