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Paper | Regular issue | Vol 60, No. 6, 2003, pp.1367-1376
Published online, 14th April, 2003
DOI: 10.3987/COM-03-9747
Synthesis of 2-(5-Amidinobenzoxazol-2-yl)-5-(4-amidinophenyl)furan and 2-(5-Amidinobenzoxazol-2-yl)-5-(4-amidinophenyl)thiophene to Test a DNA Minor Groove Dimer Binding Model

Adalgisa Batista-Parra, Sheela Venkitachalam, W. David Wilson, and David W. Boykin*

*Department of Chemistry, Georgia State University, University Plaza, Atlanta, GA 30303, U.S.A.

Abstract

Two new bis-amidines were synthesized, characterized and tested to probe the structural requirements for a DNA minor groove dimmer binding model.