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Communication | Special issue | Vol 59, No. 1, 2003, pp.87-92
Published online, 1st January, 1970
DOI: 10.3987/COM-02-S32
A Novel Route to 1,8-Dihydroxynaphthalene-derived Natural Products. Synthesis of (±)-CJ-12,372

Masayuki Inoue, Kazuyuki Nabatame, and Masahiro Hirama*

*Department of Chemistry, Graduate School of Science, Tohoku University, Aramaki, Aoba-ku, sendai 980-8578, Japan

Abstract

1,8-Dihydroxynaphthalene-derived natural products show a wide variety of biological activities, and thus have the attracted interest of both the chemical and biological communities. We report a novel and efficient approach to these natural products and its application to the total synthesis of (±)-CJ-12,372, a representative example of this class of compounds.