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Paper | Special issue | Vol 59, No. 1, 2003, pp.161-167
Published online, 1st January, 1970
DOI: 10.3987/COM-02-S10
3-Cyano-2-(N-cyanoimino)thiazolidine (3-cyano-NCT): An Efficient Electrophilic Cyanating Agent for Activated Methylene Compounds

Naoyoshi Maezaki, Akemi Furusawa, Shuji Uchida, and Tetsuaki Tanaka*

*Graduate School of Pharmaceutical Science, Osaka University, 1-6 Yamadaoka, Toyonaka, Osaka 560-0043, Japan


We found that 3-cyano-2-(N-cyanoimino)thiazolidine (3-cyano-NCT) is a novel electrophilic cyanating agent. Various activated methylene compounds were cyanated in moderate to good yields.