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Paper | Regular issue | Vol 57, No. 12, 2002, pp.2335-2343
Published online, 1st January, 1970
DOI: 10.3987/COM-02-9621
Synthesis of 7-Aminopyrazolo[3,4-c]pyridine as a Probe for the Preparation of compounds of Pharmacological Interest

Vassilios N. Kourafalos, Panagiotis Marakos, Nicole Pouli,* Aris Terzis, and Leroy B. Townsend*

*Division of Pharmaceuical Chemistry, Department of Pharmacy, University of Athens, Panepistimiopolis-Zografou, Athens GR-15771, Greece


A synthetic route towards the preparation of 7-aminopyrazolo[3,4-c]pyridine is developed, starting from the readily accessible 2-amino-4-methyl-3-nitropyridine. The unexpected formation of 7-methylimidazolo[4,5-b]pyridin-2-one during the reaction sequence is also described.