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Note | Regular issue | Vol 57, No. 11, 2002, pp.2145-2148
Published online, 1st January, 1970
DOI: 10.3987/COM-02-9584
■ High-Throughput Synthesis of Symmetrically 3,5-Disubstituted 4-Amino-1,2,4-triazoles from Aldehydes Using Microwave

Hideko Koshima,* Mitsuo Hamada, Makiko Tani, Shunsuke Iwasaki, and Fumika Sato

*Department of Applied Chemistry, Faculty of Engineering, Ehime University, 3 Bunkyo-cho, Matsuyama, 790-8577 Ehime, Japan

Abstract

Symmetrically 3,5-substituted 4-amino-1,2,4-triazoles are quickly prepared from aromatic aldehydes via nitriles by two-step reactions without any separation under microwave irradiation for each several minutes.