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Communication | Regular issue | Vol 57, No. 10, 2002, pp.1793-1797
Published online, 1st January, 1970
DOI: 10.3987/COM-02-9570
Syntheses of (4R, 5S)- and (4S, 5R)-Muricatacins, and (4S, 5R)-Aza-Muricatacin, Unnatural Analogues of the Annonaceous Acetogenin

Hiroyuki Konno,* Naoki Hiura, and Moegi Yanaru

*Department of Biological Science and Technology, Faculty of Engineering, University of Tokushima, Minamijosanjima-cho, Tokushima 770-0814, Japan


(4R, 5S)- and (4S, 5R)-Muricatacins, and (4S, 5R)-aza-muricatacin, unnatural analogues of the Annonaceous acetogenin, were prepared from (-)-muricatacin via Mitsunobu inversion or Weinreb amidation as the key step.