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Paper | Regular issue | Vol 57, No. 10, 2002, pp.1841-1850
Published online, 1st January, 1970
DOI: 10.3987/COM-02-9561
Regioselective Preparation of Pterin 6-Triflate and Its Application to 6-Substituted Pterin Synthesis

Masato Kujime, Kazunari Kudoh, and Shizuaki Murata*

*Graduate School of Environmental Studies, Nagoya University, Chikusa, Nagoya, Aichi 464-8601, Japan


4-Butoxypteridine 6-triflate is prepared selectively from 4-butoxypteridine 8-oxide by a reaction with trifluoromethanesulfonic anhydride, and the triflate group can be replaced by various nucleophiles with functional groups.