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Paper | Regular issue | Vol 57, No. 11, 2002, pp.2021-2033
Published online, 1st January, 1970
DOI: 10.3987/COM-02-9560
A Synthesis of Substituted 3,6-Dihydro-1H-benzo[c]oxocines via Claisen Rearrangement and Ring-closing Metathesis

Eng-Chi Wang,* Chin-Cheng Wang, Ming-Kun Hsu, and Keng-Shiang Huang

*School of Chemistry, Kaohsiung Medical University, 100 Shin Chuen 1st Rd., Kaohsiung 80708, Taiwan, R.O.C.


Started from isovanillin, based on Claisen rearrangement and ring-closing metathesis (RCM) reaction, a series of substituted 3,6-dihydro- 1H-benzo[c]oxocines were synthesized in moderate yields.