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Note | Regular issue | Vol 57, No. 7, 2002, pp.1319-1326
Published online, 1st January, 1970
DOI: 10.3987/COM-02-9496
Synthesis and Anticoccidial Activity of Some Azacyclo Organoborinates

Hitoshi Tabuchi, Harumoto Kawaguchi, Hisashi Taniguchi, Hideyuki Imazaki, and Yoshio Hayase*

*Nitto Kasei Co., ltd., 3-17-14 Nishiawaji, Higashiyodogawa-ku, Osaka City 533-0031, Japan


A series of azacyclo organoborinates derivatives of piperidinyl and pyridinyl alcohols were prepared and their anticoccidial activity was tested in vitro assay system. Among them, di(4-chlorophenyl)(2-piperidinylmethoxy-O,N)boron, di(3-trifluoromethylphenyl)( 2-piperidinylmethoxy-O,N)boron, di(3-trifluoromethylphenyl)(2-pyridinylmethoxy-O,N)boron, and di(3-trifluoromethylphenyl)(2-pyridinylethoxy-O,N)boron, showed moderate anticoccidial activity against Eimeria tenella.