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Paper | Regular issue | Vol 57, No. 6, 2002, pp.1109-1115
Published online, 1st January, 1970
DOI: 10.3987/COM-02-9487
Synthesis of New Friedländer Synthon and Its Application towards the Construction of Pyrido[3,2-c]acridines

Jong Keun Son, Jae Keun Son, and Yurngdong Jahng*

*College of Pharmacy, Yeungnam University, Kyongsan 712-749, Korea

Abstract

A new Friedläder synthon, 4-aminoacridine-3-carbaldehyde was prepared in 4 steps from 3-methylacridine in 38% overall yield, which was readily condensed with acetylaromatics to yield 2-arylpyrido[3,2-c]acridines.