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Paper | Regular issue | Vol 57, No. 6, 2002, pp.1101-1107
Published online, 1st January, 1970
DOI: 10.3987/COM-02-9476
Synthesis of 2,4-Disubstituted Indoles via Thermal Cyclization of N-Trifluoroacetyl Enehydrazines

Okiko Miyata, Norihiko Takeda, and Takeaki Naito*

*Kobe Pharmaceutical University, Motoyamakita, Higashinada, Kobe 658-8558, Japan

Abstract

Synthesis of naturally occurring indoles, 2,4-dimethylindole and 4-hydroxymethyl-2-methylindole by applying thermal cyclization of N-trifluoroacetyl enehydrazines is described.