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Communication | Special issue | Vol 58, No. 1, 2002, pp.43-46
Published online, 1st January, 1970
DOI: 10.3987/COM-01-S(M)6
Highly Functionalized Pyrans Designed for Multipoint Side Chain Attachment to the F-Ring Sector of Spongistatin 1 (Altohyrtin A)

Il Hwan Cho and Leo A. Paquette*

*Evans Chemical Laboratories, The Ohio State University, 120 W. 18th Avenue, Columbus, Ohio 43210, U.S.A.


The synthesis of three potential F-ring components, variably functionalized for attachment to the chlorodiene side chain by differing chemical means, has been accomplished from D-(+)-mannose as the generic precursor.