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Paper | Special issue | Vol 56, No. 1-2, 2002, pp.387-392
Published online, 1st January, 1970
DOI: 10.3987/COM-01-S(K)56
A Highly Sensitive and Specific FDCD Method for Chirality Analysis of Naturally Occurring Pteridines

Ning Chen, Kazuhisa Ikemoto, Takashi Sugimoto, Shizuaki Murata,* Hiroshi Ichinose, and Toshiharu Nagatsu

*Graduate School of Environmental Studies, Nagoya University, Chikusa, Nagoya, Aichi 464-8601, Japan


Absolute configurations of 6-(1-hydroxyalkyl)pterin derivatives are determined by fluorescence detected circular dichroism (FDCD) spectroscopy. This method is at least 10 times more sensitive than CD analysis and specific even existence of 10 times excess amounts of chiral sugars or nucleic acids.