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Communication | Special issue | Vol 56, No. 1-2, 2002, pp.101-103
Published online, 1st January, 1970
DOI: 10.3987/COM-01-S(K)49
Three-Step Total Synthesis of Pyrroloquinazolinoquinoline Alkaloid, Luotonin A, by Intramolecular Hetero Diels-Alder Reaction

Masahiro Toyota,* Chiyo Komori, and Masataka Ihara*

*Department of Organic Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Aobayama, Sendai 980-8578, Japan


Total synthesis of luotonin A (1) was accomplished, starting from 3-aminomethyl-2-bromoquinoline (4) in three steps via intramolecular hetero Diels-Alder reaction.