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Note | Regular issue | Vol 57, No. 4, 2002, pp.715-721
Published online, 1st January, 1970
DOI: 10.3987/COM-01-9430
Two New Withanolides from the Aerial Parts of Datura innoxia

Bina S. Siddiqui,* Imran Ali Hashmi, and Sabira Begum

*International Centre for Chemical Sciences, H. E. J. Research Institute of Chemistry, University of Karachi, Karachi-75270, Pakistan


Two new withanolides named as withametelinol-A (1) and withametelinol-B (2) have been isolated from the aerial parts of Datura innoxia. Their structures have been elucidated as (20R, 22R)-21,24-epoxy-5β-hydroxy-1-oxowitha-2,9(11),25(27)-trienolide and (20R, 22R)-21,24-epoxy-12α-hydroxy-1-oxowitha-3,5,25(27)-trienolide respectively through spectroscopic studies.