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Communication | Regular issue | Vol 55, No. 8, 2001, pp.1451-1454
Published online, 1st January, 1970■ Stereocontrolled Synthesis of 3-Hydroxy-2,3,4,5-tetrahydro-1,5-benzothiazepines by Means of Neighboring Group Participation
Published online, 1st January, 1970
DOI: 10.3987/COM-01-9273
■ Stereocontrolled Synthesis of 3-Hydroxy-2,3,4,5-tetrahydro-1,5-benzothiazepines by Means of Neighboring Group Participation
Michinori Karikomi, Kozue Ayame, and Takashi Toda*
*Department of Applied Chemistry, Faculty of Engineering, Utsunomiya University, 7-1-2 Yoto, Utsunomiya 321-8585, Japan
Abstract
A novel stereocontrolled synthesis of 3-hydroxy-2,3,4,5-tetrahydro-1,5-Benzothiazepines (4) by means of neighboring group participation is described. The influence of solvents, additives, and substituents is also discussed.
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