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Paper | Regular issue | Vol 55, No. 6, 2001, pp.1105-1111
Published online, 1st January, 1970
DOI: 10.3987/COM-01-9200
New Synthetic Approach to Pyridazino[4,5-b]indoles by Pd(0)-catalyzed Cross-Coupling Reaction

Gábor Krajsovszky, Péter Mátyus, Zsuzsanna Riedl, Dorottya Csányi, and György Hajós

*Chemical Research Center, Institute of Chemistry, Hungarian Academy of Sciences, H-1525 Budapest, P.O.Box 17, Hungary


5-Iodo-2-methylpyridazin-3(2H)-one readily underwent Suzuki coupling with protected anilinoboronic acids to yield the corresponding arylpyridazinones which proved to be suitable starting compounds to a ring closure — a 4 step pathway — to pyridazino[4,5-b]indoles.