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Note | Regular issue | Vol 55, No. 6, 2001, pp.1127-1132
Published online, 1st January, 1970
DOI: 10.3987/COM-01-9187
Tandem Cyclization of Phytosphingosine

Su Yeon Jo, Hyoung Cheul Kim, Dong Ju Jeon, and Hyoung Rae Kim*

*Bio-Organic Division, Korea Research Institute of Chemical Technology, P. O. Box 107, Yusong, Taejon 305-606, Korea


Phytosphingosine is easily cyclized during the protection of amino group with phthalic acid derivatives to form trisubstituted tetrahydrofuran structure (2) by the attack of 4-hydroxyl group to the terminal carbon. The structure of compound (2) was confirmed by X-Ray crystallography and synthetic method.