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Communication | Regular issue | Vol 55, No. 5, 2001, pp.847-850
Published online, 1st January, 1970
DOI: 10.3987/COM-01-9179
Thermodynamically Controlled Deracemization of 2-Alkylcycloalkanones Utilizing Host-Guest Inclusion Complexation

Hiroto Kaku, Shinobu Ozako, Shiho Kawamura, Shinobu Takatsu, Masayuki Ishii, and Tetsuto Tsunoda*

*Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 180 Nishihamabouji, Yamashiro-machi, Tokushima, 770-8514, Japan


Based on host-guest inclusion complexation in the solid state, α-substituted cycloalkanones were deracemized using optically active host compound, TADDOL (2a) in alkaline conditions.