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Communication | Regular issue | Vol 55, No. 4, 2001, pp.623-627
Published online, 1st January, 1970
DOI: 10.3987/COM-01-9153
On the Synthesis and Reactivity of 1-Benzyl-2-arylquinoline-4-thiones

Edmund J. Niedzinski, Matthew R. Lashley, and Michael H. Nantz*

*Department of Chemistry, University of California, Davis, One Shields Avenue, Davis, CA 95616-5295, U.S.A.

Abstract

A panel of 1-benzyl-2-aryl-4-quinolones was synthesized in three steps and converted to the corresponding 4-thione derivatives using Lawesson’s reagent. The representative vinylogous thioamide (5a) was alkylated to afford a novel series of quinolinium salts.